Treating neurological disease with diet
Scientific papers about ketogenic diet

Recent review article
Freeman JM, Kossoff EH.
Ketosis and the ketogenic diet, 2010: advances in treating epilepsy and other disorders.
Adv Pediatr.

Early paper on ketogenic diet by the man who thought up the idea
Wilder RM, Winter MD.
The threshold of ketogenesis.
J Biol Chem.
1922 52:393–401.

First paper on ketogenic diet by the man who devised the first version of it
Peterman MG.
The ketogenic diet in the treatment of epilepsy: a preliminary report.
Am J Dis Child.
1924;28 :28–33 .

Review paper about medium-chain triglycerides
Bach AC, Babayan VK.
Medium-chain triglycerides: an update.
Am J Clin Nutr.
192 Nov;36(5):950–62.

Branched chain amino acids
Evangeliou A, Spilioti M, et al.
Branched chain amino acids as adjunctive therapy to ketogenic diet in epilepsy: pilot study and hypothesis.
J Child Neurol 2009 Oct;24(10):1268-72. Epub 2009 Aug 17.

Good review article; discusses diseases besides epilepsy
Freeman JM, Kossoff EH, Hartman AL.
The ketogenic diet: one decade later.
. 2007 Mar 1; 119(3): 535–543.

A long conference review on medical keto diets from 2005
Freeman J, Veggiotti P, Lanzi G, Tagliabue A, Perucca A
The ketogenic diet: From molecular mechanisms to clinical effects.
Epilepsy Research.
2008; 68: 145–180.

Atkins diet for epilepsy
Kossoff EH, McGrogan JR, Bluml RM, Pillas RM, Pillas DJ, Rubenstein JE, Vining EP.
A Modified Atkins diet is effective for the treatment of intractable pediatric epilepsy
Epilepsia. 2006;47:421–424.

Neuropharmacology of ketogenic diet
.Hartman AL, Gasior M, Vining EP, Rogawski MA.
The neuropharmacology of the ketogenic diet
Pediatric Neurology.
2007 May;36(5):281–92.

MCT as a treatment for Alzheimers disease
Newport M. What if there was a cure for Alzheimer's disease and no one knew it?

MCT oil as a treatment for Alzheimers disease
This patent application includes a discussion of the effects of medium-chain triglycerides on brain metabolism. Hat tip to Dr. Mary Newport.

This page was last revised on July 20, 2011